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BY INVITATION ONLY - REGISTER BY JUNE 21, 2019.

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Monday, July 1 • 2:30pm - 2:45pm
How druggable is the transcriptome? Finding small molecule binding sites in RNA.

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Despite our increasing appreciation of non-coding RNA function, RNA has been conspicuously underrepresented in small-molecule drug development efforts until recently. Now it is clear binding pockets on RNA can make good drug targets, yet the properties and principles of small molecule binding sites on RNA remain poorly defined. I will discuss the challenges of defining small-molecule binding sites across the transcriptome and new approaches to address these challenges.

Speakers
avatar for Matthew Simon, PhD

Matthew Simon, PhD

Associate Professor of Molecular Biophysics and Biochemistry, Yale University
Matt grew up in Ann Arbor, MI and received his Ph.D. in Chemistry from UC Berkeley. He commuted between Berkeley and UCSF, working with Kevan Shokat developing chemical methods to make synthetic chromatin substrates to study the biochemistry of epigenetics. He continued this work... Read More →


Monday July 1, 2019 2:30pm - 2:45pm EDT
Abigail Adams Salon A/B